Biochemical profile of diabetic patients in a private laboratory in southern Brazil

  • Miriãn Ferrão Maciel FIUZA Laboratório de Biociências, Curso de Biomedicina, Universidade Franciscana, Santa Maria, RS, Brasil
  • Natielen Jacques SCHUCH Laboratório de Biociências, Curso de Nutrição e Mestrado em Ciências da Saúde e da Vida, Universidade Franciscana, Santa Maria, RS, Brasil
  • Ana Cláudia Cirne BERNDT Laboratório de Análises Clínicas Pasteur
  • Clandio Timm MARQUES Área Tecnológica, Curso de Matemática e Programa de Pós-Graduação em Ensino de Ciências e Matemática, Universidade Franciscana, Santa Maria, RS, Brasil
  • Luciana Maria Fontanari KRAUSE Laboratório de Biociências, Curso de Biomedicina e Mestrado em Ciências da Saúde e da Vida, Universidade Franciscana, Santa Maria, RS, Brasil
Keywords: cholesterol, diabetes, epidemiology, blood glucose, HbA1c

Abstract

Diabetes is a chronic disease characterized by the presence of permanent hyperglycemia. GlycatedHemoglobin (HbA1c) is formed through the non-enzymatic binding of hemoglobin and glucose. Itsdosage in blood is one of the most relevant factors in the evaluation of the glycemic control. The aimof this study is to correlate age, glycemic and lipid profiles in a sample of 776 patients diagnosed withDiabetes Mellitus (DM), from a laboratory in southern Brazil. A total of 776 medical records wereanalyzed between January and March 2018, and the records were obtained from the records of themonths between March 2016 and March 2018. HbA1c, glucose, triglyceride, total cholesterol, LDLcholesteroland HDL-cholesterol values were analyzed. Our results show a predominance of elderlywomen (61%), with no age variation between genders, in both it was possible to observe negative andsignificant correlation between age and LDL-C. There was no clear association between HbA1c andlipid profile. The results showed increased levels of HbA1c and a reduction in total cholesterol andLDL-C in patients over 60 years. A strong positive correlation was found between HbA1c and glucoseparameters in both genders. The correlations between age and other variables were weak between both.

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Published
2021-04-16
How to Cite
FIUZA, M. F. M., SCHUCH, N. J., BERNDT, A. C. C., MARQUES, C. T., & KRAUSE, L. M. F. (2021). Biochemical profile of diabetic patients in a private laboratory in southern Brazil. Revista Do Instituto Adolfo Lutz, 79(1), e1782. Retrieved from https://periodicoshomolog.saude.sp.gov.br/index.php/RIAL/article/view/35479
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ORIGINAL ARTICLE