Opsonization and transformation: effects of anticapsular sera on the DNA transfer in Neisseria meningitidis

  • Gisele Cristiane Gentile Cury Universidade Estadual de Campinas, Instituto de Biologia, Campinas, SP
  • Rafaella Fabiana Carneiro Pereira Universidade Estadual de Campinas, Instituto de Biologia, Campinas, SP
  • Luciana Maria de Hollanda Universidade Estadual de Campinas, Instituto de Biologia, Campinas, SP
  • Marcelo Lancellotti Universidade Estadual de Campinas, Instituto de Biologia, Campinas, SP
Keywords: Neisseria meningitidis, transformation, opsonization, capsule

Abstract

The capsular switching process indicates the action of specific capsular antibodies on the meningococcal strains adaptation. Different antibodies were employed for assessing the effect of opsonization on the transformation of Neisseria meningitidis serogroups C and W135. These analyses showed the blocking action of the specific capsular antibodies on the meningococcal transformation capacity. Thus, the blocking effect of these antibodies on N. meningitidis transformation process was demonstrated. This effect could be involved in the capsular switching process and the found data might open new subjects for scientific exploration.
Published
2012-03-01
How to Cite
Cury, G. C. G., Pereira, R. F. C., Hollanda, L. M. de, & Lancellotti, M. (2012). Opsonization and transformation: effects of anticapsular sera on the DNA transfer in Neisseria meningitidis. Revista Do Instituto Adolfo Lutz, 71(3), 605-607. Retrieved from https://periodicoshomolog.saude.sp.gov.br/index.php/RIAL/article/view/32472
Issue
Vol. 71 No. 3 (2012)
Section
SCIENTIFIC NOTE